Jannat Phonphet. The study of factors affecting the health status in patients with coronary heart disease : at Phathalung hospital. Bangkok : Mahidol University, 2001. 76 p. T E17160.
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Knowledge about the geographic distribution of filarial infection had long been limited by a phenomenon known as periodicity, whereby the concentration of microfilariae in the peripheral blood fluctuates dramatically with time of day, being greatest during the peak feeding time of the mosquito vector and frequently undetectable when the mosquito is not active.
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Ph.D., 1 William Ascher, San Diego State University, San Diego, CA; 2Government and Economics, Claremont McKenna College, Claremont, CA; and 3Nutrition and Physical Activity, Centers for Disease Control and Prevention, Atlanta, GA. A broad range of policies from government, corporate, and non-profit organizations are believed to affect physical activity. For example, zoning laws affect the pedestrian-friendliness of community design, school policies affect the availability of schools for physical activity outside of school hours, and policies of insurance companies control incentives for being physically active. Few studies have examined the relation between policy and physical activity, but such studies are needed to identify policy changes with the potential to increase physical activity in the population. The Centers for Disease Control and Prevention CDC ; and The Robert Wood Johnson Foundation's Active Living Research Program ALR ; have initiatives to fund physical activity policy studies. Because most behavioral medicine researchers have limited experience with policy research, this Seminar is designed to prepare investigators to develop competitive proposals. James Sallis and Tom Schmid will describe physical activity policy research priorities at CDC and ALR, including upcoming Calls for Proposals. Tom Schmid will present a definition and model of physical activity policy research, describe CDC's policy research agenda, and outline CDC WHO efforts to promote physical activity through development of national physical activity policies. William Ascher will provide an overview of the policy research field, including common study designs and methods. He will offer guidance on policy research journals, professional organizations, leading training programs, and how to identify appropriate collaborators. Written materials will be distributed, and there will be ample opportunities for question and answer. CORRESPONDING AUTHOR: James F. Sallis, PhD, Psychology, San Diego State University, 3900 Fifth Avenue, Suite 310, San Diego, CA, USA, 92103; sallis mail.sdsu.
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If you have observed any suspected ADRs with the drugs in the Communiqu or the DOCI list, please report them to the : Adverse Drug Reaction Reporting Unit Continuing Assessment Division Bureau of Drug Surveillance AL 0201C2, Ottawa, ON K1A 1B9 Fax: 613 957-0335; or to a participating regional ADR centre. The ADR form is available at and serevent.
En 26 ; En 99309679.1 22 ; 02.12.1999 DE FR GB 14.06.2000 10.12.1998 US 209515 Silikonemulsionen mit stabilen Korngrossen Particle size stable silicone emulsions Emulsions de silicones a granulometrie stable ` 73 ; DOW CORNING CORPORATION, 3901 S. Saginaw Road, Midland, Michigan 48686-0994, US 72 ; Gee, Ronald Paul, Midland, Michigan 48640, US 74 ; Kyle, Diana, et al, Elkington and Fife LLP, Prospect House 8 Pembroke Road, Sevenoaks, Kent TN13 1XR, GB.
Of sulfamethoxazole at 250 mg kg per day and trimethoprim at 50 mg kg per day used by other investigators in the treatmient of experimental pneumocystosis in rats 14, 21 ; was highly effective in our model. The median histologic score fell from 3 + in the control steroid group to 0 in the treated group; P. carinii cyst and nuclei counts declined from 5.09 x 108 and 9.11 x 108 per lung, respectively, to 1.64 x 106 and -1.47 x 105 per lung, respectively. Similar results were found when the same dose of sulfamethoxazole was used alone or combined with diaveridine at 50 tng kg per day or when these drugs were used in higher dose regimens. In an effort to demonstrate drug synergy, sulfamethoxazole was tested at the low dose of 62.5 mg kg per day alone and in combination with trimethoprim at 12.5 mg kg per day. The median histologic score and cyst count in the sulfamethoxazole-treated rats were 0.75 + and 6.91 x 106 cysts per lung, respectively, compared with 0.5 + and 4.41 x 105 cysts per lung, respectively, in the rats, suggesting that trimethoprim had only a slight effect on therapeutic activity. The sulfamethoxazole regimens were well tolerated, with all rat groups having a median duration of therapy of 20 to days. Sulfadiazine. Sulfadiazine was very active in the treatment of rat pneumocystis Fig. 2 ; . When used alone in the dose of 250 mg kg per day or combined with diaveridine or trimethoprim in a dose of 50 mg kg per day, the drug resulted in a fall in the median histologic score from 4 + in the steroid controls to 0 to 0.5 + in the treated groups. Median cyst counts declined from 8.03 x 108 cysts per lung to 6.62 x 105 cysts per lung in the sulfadiazine-treated rats and 1.91 x 106 cysts per lung in the sulfadiazine-trimethoprim-treated rats, respectively, and similar changes occurred with the nuclei counts. Comparable therapeutic efficacy was found when sulfadiazine was used with diaveridine at 50 mg kg per day or when higher drug dose combinations of these agents were used. Sulfadiazine caused no detectable adverse reactions in and serzone, for example, effects rohypnol.
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1. ACTION CODE: Key in one of the following codes: A is add; C is change; D is delete; I is inquiry; or L is DUR list. Again, only an ACS clinical pharmacist has access to add or change a drug record; all other system users have inquiry-only access to the Drug File. Therapeutic Class inquiry and updating is available only for DUR Filter records. 2. DUR FILTER: Entry point for setting DUR conflict codes to pay, deny, or ignore based on specific criteria. Please refer to the DUR FILTER information section later within this chapter to read more on this subject. NOTE: DUR Filter inquiries or updates may be made by Generic Code Number or Therapeutic Class only. 3. There are several ways a drug record can be accessed in PDCS: The National Drug Code NDC Drug Name; Generic Sequence Number GSN or Generic Code Number GCN ; . Enter only one selection at a time for options A through E and singulair.
Palan PR, Magneson AT, Castillo M, Dunne J, Mikhail MS. Department of Obstetrics and Gynecology, Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, NY, USA. daspalan aol Effects of menstrual cycle and oral contraceptive use on serum levels of lipid-soluble antioxidants. J Obstet Gynecol. 2006 May; 194 5 ; : e35-8. Epub 2006 Apr 21. OBJECTIVE: The purpose of this study was to examine the influence of menstrual cycle and oral contraceptive use on serum levels of lipid-soluble antioxidants. STUDY DESIGN: In this cross-section study, nonfasting blood samples were collected twice from 10 healthy premenopausal women during the follicular phase between days 8 and 11 ; and the luteal phase between days 18 and 22 ; of their same menstrual cycle. In addition, blood samples from 15 premenopausal women who used oral contraceptive for at least 6 months and 40 women who did not use oral contraceptive were collected randomly at any day of the menstrual cycle. Serum levels of coenzyme Q10, alpha-tocopherol, gamma-tocopherol, beta-carotene, alpha-carotene, and lycopene were determined using high pressure liquid chromatography. RESULTS: Serum coenzyme Q10 and alpha-tocopherol levels were significantly lower during the follicular phase compared with the luteal phase of the same menstrual cycle P .05 ; . Oral contraceptive use also significantly decreased coenzyme Q10 and alpha-tocopherol P .001 ; . Other antioxidant levels were comparable. CONCLUSION: Alterations in coenzyme Q10 and alpha-tocopherol levels during the menstrual cycle and in oral contraceptive users should be taken into consideration, concerning the future antioxidant research in premenopausal women. Further studies are needed to investigate the potential role of endogenous and exogenous ovarian hormones on oxidative stress in women. Sharma JB, Kumar A, Kumar A, Malhotra M, Arora R, Prasad S, Batra S. Department of Obstetrics and Gynecology, Maulana Azad Medical College and associated Lok Nayak Hospital, New Delhi, India. jbsharma eth Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol Obstet. 2003 Jun; 81 3 ; : 257-62. OBJECTIVES: To observe the effect of the antioxidant lycopene on the occurrence of pre-eclampsia and intrauterine growth retardation in primigravida women. METHODS: A total of 251 primigravida women were enrolled in this prospective, randomized controlled study in the second trimester. A total of 116 women were given oral lycopene Group I ; in a dose of 2 mg twice daily while 135 women were given a placebo Group II ; in the same dose until delivery. The criteria for recruitment included gestational age of 16-20 weeks, singleton pregnancy, absence of any medical complication and willingness on the part of the women to participate in the study. The women were followed-up until delivery for development of pre-eclampsia, mode of delivery and fetal outcome. RESULTS: The two groups were comparable in their maternal characteristics. Pre-eclampsia developed in significantly less women in the lycopene group than in the placebo group 8.6% vs. 17.7%, P 0.043 by chi-square test ; . Mean diastolic blood pressure was significantly higher in the placebo group 92.2 + -5.98 mmHg vs. 86.7 + -3.80 mmHg, P 0.012 ; . Mean fetal weight was significantly higher in the lycopene group 2751.17 + -315.76 g vs. 2657 + -444.30 g, P 0.049 ; . The incidence of intrauterine growth retardation was significantly lower in the lycopene group than in the placebo group 12% vs. 23.7%, P 0.033 ; . CONCLUSIONS: The results of the present study suggest that the antioxidant lycopene reduces the development of pre-eclampsia and intrauterine growth retardation in primigravida women.
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Slater, T. F. 1972b ; , in A Companion to Biochemistry Bull, A. T., Lagnado, J. R., Thomas, J. 0. & Tipton, K. F., eds. ; , pp. 511-551, Longmans Green, London. Slater, T. F. 1976 ; in Recent Advances in Biochemical Pathology: Toxic Liver Injury Dianzani, M. U., Ugazio, G. & Sena, L. M., eds. ; , pp. 99-108, Minerva Medica, Torino Slater, T. F. 1982 ; in Free Radicals, Lipid Peroxidation and Cancer McBrien, D. C. H. & Slater, T. F., eds. ; , pp. 243270, Academic Press, London Slater, T. F. 1987 ; Agents Actions 22, 333-334 Slater, T. F. & Sawyer, B. C. 1969 ; Biochem. J. 111, 317-324 Slater, T. F. & Sawyer, B. C. 1971a ; Biochem. J. 123, 805-814 Slater, T. F. & Sawyer, B. C. 197 lb ; Biochem. J. 123, 815-821 Slater, T. F. & Sawyer, B. C. 1971c ; Biochem. J. 123, 823-828 Smith, M. T. & Sandy, M. S. 1985 ; Toxicol. Appl. Pharmacol. 81, 213-219 Uzanov, P., Shein, H. M. & Weiss, B. 1974 ; Neuropharmacology 13, 377-391 and synthroid.
In the next set of examples, BioCo wishes to license one or more pharmaceutical or biotech companies that own competing AIB patents to manufacture and or distribute ImmuCan. There are five other independently controlled AIB technologies comparable to ImmuCan. Moreover, there are a number of firms that have the capability to manufacture ImmuCan and other AIBs. BioCo is contemplating several different potential arrangements.
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My appetite is: Minimal Normal Excessive My weight has changed during this period of low mood. No Yes Explain I move: Slower than normal Faster than normal Normal speed I hopeful about my future: True False I have extremely high excessively happy ; moods that others notice: All the time Sometimes Never During these markedly elevated moods: 1. I feel grandiose special, very self confident, feel like I can do extraordinary things ; Yes No N A irritable. Snapping at others for no reason, starting fights ; Yes No 3. People have thought I was using drugs when I wasn't. Yes No 4. I start many projects. Yes No 5. I get distracted easily and don't finish what I start. Yes No 6. I don't need to sleep much. Yes No 7. I have racing thoughts which I cannot control. Yes No C. Couts, M.D, for instance, flunitrazepam.
Don't accept drinks from other people, except trusted friends. Open containers yourself. Keep your drink with you at all times, even when you go to the bathroom. Don't share drinks. Don't drink from punch bowls or other large, common, open containers. They may already have drugs in them. Don't drink anything that tastes or smells strange. Sometimes, GHB tastes salty. Have a non-drinking friend with you to make sure nothing happens. If you think that you have been drugged and raped: o Go to the police station or hospital right away. o Get a urine pee ; test as soon as possible. The drugs leave your system quickly. Dohypnol leaves your body 72 hours after you take it. GHB leaves the body in 12 hours. o Don't urinate before getting help. o Don't douche, bathe, or change clothes before getting help. These things may give evidence of the rape. o You also can call a crisis center or a hotline to talk with a counselor. One national hotline is the National Domestic Violence Hotline at 800-799-SAFE or 800-787-3224 TDD ; . Feelings of shame, guilt, fear and shock are normal. It is important to get counseling from a trusted professional and temazepam.
According to the Washington Association of Sheriffs and Police Chiefs, the following arrests were reported for 2001 for drug law violations: % of Drug Arrests White Black Native American Asian 80.0% 15.9% 2.1% % of General Population 83.4% 3.0% 1.4% In the City of Seattle, arrests for drug violations in 2001 were as follows: # of Drug Arrests White Black Native American Asian 1, 798 2, % of Drug Arrests 42.7% 51.9% 2.0% Of all felony drug convictions in state courts throughout the United States in 1998, 53% were of African Americans and only 46% were of Caucasians, with "Hispanics" included in the "White" category. Similarly, of all drug offenders currently in state prisons across the United States, 57.9% are African-American, 23.2% are Caucasian and 17.2% are Hispanic, for instance, inhalants.
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OBJECTIVES 1 ; To review the importance of secondary ischemic injury after head injury; 2 ; To discuss the anesthetic management of acutely head-injured patients; and 3 ; To review current evidence-based guidelines for intensive care of head-injured patients. CASE PRESENTATION INTRODUCTION Perioperative management of patients with traumatic brain injury TBI ; is guided by the imperative to avoid increasing the burden of secondary brain injury that is added to primary brain injury. Two strategies are essential in reducing secondary brain injury: 1. Promptly restore and maintain systemic cardiopulmonary stability 2. Monitor physiologic variables that reflect potential secondary injury and promptly intervene After severe TBI, secondary brain injury contributes to adverse outcome. Secondary brain injury, assumed to be ischemic in origin, is associated with postinjury hypotension, hypoxemia, and intracranial hypertension. Contributing mechanisms include cerebral vasoconstriction especially in the first few hours after TBI ; and impaired pressure autoregulation of the cerebral circulation. Chesnut et al.1 reported that hypotension systolic blood pressure 90 mm Hg ; after severe TBI dramatically reduced the likelihood of favorable outcome Table 1 ; . Table 1. Influence of Early Admission ; or Late Intensive Care Unit ; Hypotension on Outcome After Severe TBI Outcome % ; Hypotension n ; GR or SD, PVS, or Death None 307 64 36 Early 30 40 60 Late 117 20 80 Early and late 39 15 85 GR, good recovery; MD, moderate disability; SD, severe disability; PVS, persistent vegetative state. From Chestnut RM.1 To minimize mortality and morbidity, severely head-injured patients require effective preoperative, intraoperative, and postoperative management, especially prevention and prompt treatment of hypotension.1 Information that is useful in managing these patients is available from a recent text2 and a comprehensive set of practice guidelines.3 CEREBRAL CIRCULATORY RESPONSES TO ACUTE HEAD INJURY TBI is characterized by reduced cerebral blood flow CBF ; , impaired cerebral pressure autoregulation and increased intracranial pressure ICP ; . In one-third of 106 head-injured patients injured six or fewer hours previously, CBF was 18 mL 100g-1 min-1 the threshold for cerebral ischemia ; .4 The cerebral arteriovenous oxygen content difference systemic arterial oxygen content - jugular venous bulb oxygen content ; was abnormally high in the first few hours after injury and then progressively decreased.4 Hyperventilation may further reduce CBF and reduce brain oxygenation.5 and terazosin.
We note that the Shareholders' Mandate will not cover any Interested Person Transaction that is below S$100, 000 in value as the threshold and aggregation requirements of Chapter 9 of the Listing Manual would not apply to such transactions. The details of the above Interested Person Transactions are set out in the section "Interested Person Transactions and Conflicts of Interests" of the Prospectus. 3.3 Guidelines and Review Procedures for Interested Person Transactions The detailed text of the review procedures for the Interested Person Transactions can be found in the section "Guidelines and Review Procedures for Interested Person Transactions under the Shareholders' Mandate" of the Prospectus. We note, inter alia, the following procedures established by the Group: The Group has implemented the following procedures to ensure that the Interested Person Transactions are undertaken at arms' length and on normal commercial terms and consistent with the usual business practices and policies, which are generally no more favourable than those extended to unrelated third parties where applicable.
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NASOENTERAL FEEDING TUBES A nasoenteric tube is indicated for short-term use, usually less than 30 days. Nasoenteral tubes are inserted through the nose and advanced through the esophagus into the stomach nasogastric tube ; , the duodenum nasoduodenal tube ; , or jejunum nasojejunal tube ; . The tube is identified by the distal location of its tip. Most nasoenteric tubes are soft, flexible, small-bore polyurethane or silicone tubes that are 8 to 14 French in diameter, 20 to 60 inches in length, and radiopaque to allow for radiographic confirmation of placement. The shorter lengths are used for nasogastric feedings, and the longer for nasoduodenal or nasojejunal feedings. As a general rule, the smallestdiameter tube of appropriate length is preferred because the smaller diameter has been associated with less complications and increased patient comfort. Small-diameter tubes may help to prevent reflux and lessen the risk of aspiration because the small diameter lessens compromise of the lower esophageal sphincter LES ; . In addition, small-diameter tubes cause less inhibition of swallowing, which is more comfortable for patients. Tubes made of polyvinyl chloride are less desirable because, over time, they can stiffen in the presence of acid, which can lead to patient discomfort and increased complications such as tube perforation ; .10 Any nasally placed tube can cause sinusitis, erosion of the nasal septum or esophagus, epistaxis, or distal esophageal strictures, which may limit long-term use. Small, soft-bore tubes are less likely to cause these complications. Most nasoenteric tubes have multiple ports staggered along their sides and tip, which minimize clogging and maximize flow. Many devices also have weighted tips and a stylet, which stiffens the tube to assist in placement. Another common feature of many nasoenteric tubes is a "Y port" at the proximal tip, which allows for the administration of medications and irrigation without interrupting tube feeding. Types of Nasoenteric Tubes Nasogastric Tubes. Gastric feedings through a nasogastric tube are appropriate for patients who have intact gag and cough reflexes and adequate gastric emptying and tobradex and rohypnol, for example, ghb gbl.
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Medicare is a federally financed and administered health insurance program primarily for those age 65 and over, although certain other groups may also be covered. It offers time limited coverage associated with post-acute care. Post-acute care helps patients after an illness and assumes recovery. When recovery is not expected, the patient will need what is called chronic care. The actual services provided under post-acute and chronic care are often the same. What is different is that Medicare does not cover chronic care even if the service is the same and toprol.
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Patients Inappropriate for Helicopter Transport 1. 2. Patients who weight more than 250 lbs. Patients with a potential altered mental status emotion disorders, drug alcohol abuse, or general agitation ; Patients with acute CHF, acute MI, and any patient who must be positioned with the head and upper body elevated Patients who express fear of specific aversion to air transport Any patient who, in the judgment of the EMT, is potentially inappropriate and serevent.
Ginkgo biloba Special Extract EGb 761 in dementia of the vascular and Alzheimer type]. Z Gerontol Geriatr 1996; 29: 302-9. Kanowski S, Herrmann WM, Stephan K, Wierich W, Horr R. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharmacopsychiatry 1996; 29: 47-56. Le Bars PL, Katz MM, Berman N, Itil TM, Freedman AM, Schatzberg AF. A placebo controlled, double-blind, randomized trial of an extrakt of Ginkgo biloba for dementia. North American EGb Study Group. JAMA 1997; 278: 1327-32. Le Bars PL, Kieser M, Itil KZ. A 26week analysis of a double-blind, placebocontrolled trial of the ginkgo biloba extract EGb 761 in dementia. Dement Geriatr Cogn Disord 2000; 11: 230-7. Maurer K, Ihl R, Dierks T, Frolich L. Clinical efficacy of Ginkgo biloba special extract Egb 761 in dementia of the Alzheimer type. J Psychiatr Res 1997; 31: 645-55. Heuser I, Heuser-Link M, Gotthardt U, Grasser A, Holsboer F. Behavioral effects of a synthetic corticotropin 4-9 analog in patients with depression and patients with Alzheimer's disease. J Clin Psychopharmacol 1993; 13: 171-4. Soininen H, Koskinen T, Helkala EL, Pigache R, Riekkinen PJ. Treatment of Alzheimer's disease with a synthetic ACTH 4-9 analog. Neurology 1985; 35: 1348-51. Partanen JV, Soininen H, Riekkinen PJ. Does an ACTH derivative Org 2766.
And information, developing better clinical guidelines, and redesigning basic benefit packages and payment methods under social insurance programs to create incentives for both consumers and providers to rationalize drug utilization. The most remarkable characteristic of the Turkish health spending patterns and health system structure is the fact that different social security funds performed so differently, both in terms of per capita drug expenditure and drug expenditure as share of total health spending. The average drug spending level among the GERF beneficiaries is the highest, followed by active civil servants, Bag-Kur, SSK, and Green Card holders. Without detailed data on the membership characteristics e.g. their age structure and health status, etc. ; , we cannot ascertain the extent to which the differences can simply be explained by the differential in the underlying healthcare needs. However, given the significant differences in average drug expenditure, in addition to rate of increase in drug expenditure as share of total health expenditure, we suspect that the differences can be at least partially explained by different demand-side and supply-side constraints, which are related to the different financing and organizational structure of the different social security schemes. Covering more than 35 million people about 50% of the Turkish population ; , in terms of overall social security coverage but not health care coverage which is reported to be around 67% of the total population according to recent studies ; , SSK is the largest social security fund. What is interesting about SSK is its ability to keep the average drug expenditure relatively low. Several factors may help explain this. SSK operates under the Ministry of Labor and Social Security and serves principally private sector employees and blue-collar workers of the public sector. Besides operating a drug manufacturing facility, SSK used to have its own hospitals and pharmacies within hospitals and directly purchases from manufacturers, importers and wholesalers via tenders. The majority of SSK outpatient dispensing used to be done at hospital pharmacies, before this was changed from February 2005 onwards, and SSK members are now able to fill their prescriptions in community pharmacies. SSK tenders are subject to the public procurement law, and the tenders are published on SSK's website daily. In essence, SSK is operating under a global budgeting mechanism. Its comprehensive system of procurement and provider payment, as well as extensive network of healthcare delivery and distribution of pharmaceuticals, all contributed to its lower level of health expenditure in general and drug expenditure in particular. On the other hand, there is a concern that SSK may have achieved cost savings at the expense of providing inferior access to and sub-standard quality of services for its members. As Turkey is transforming its health system and thinking of developing a universal health insurance system, it would be critically important to examine the pros and cons of Turkey's.
Introduction: The complications of antithyroid agents are known. We have summarized our experience with some more memorable complications occuring with these agents Patients Methods: We have treated several hundreds of patients referred to endocine clinics with these agents over the last 39 years. The patients presented in this communication represent those with a special aspect. Results: Two patients developed agranulocytosis A ; and died during hospitalization. Two patients had 2 febrile episodes within a week. A was detected on the second episode. A developed in a single patient during a relapse of his disease treated with the same agent A developed in a single subject following administration of both PTU and Mercaptozle. A developed after two years treatment with PTU in one subject. One patient developed A and jaundice. Drug fever developed in one patient. A single patient became jaundiced with a maximal bilirubin of 20mg. He responded to I 131 while still jaundiced. Over 20 patients developed polyarthralgia, In one, RA develop a year after cessation of the agent. A drug eruption developed in one subject but PTU was continued. The rash resolved but this was followed by the appearance of polyarthralgia. A single patient developed a pleural effusion with detection of LE cells in the fluid. On stopping PTU the effusion resolved. A single patient developed hypoglycemia with adminisration of PTU. This resolved on cessation of tPTU Conclusions: The endocrinologist will meet many of the complications of these agents. He or she One must be sure the patients comprehends the potential severity of these reactions. One cannot rely on the family physician to rely the message. Most of the reactions are minor but some may be life threatening and need to be remembered.
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