The methanolic extract of Ficus platyphylla Del.-Holl. stem bark was investigated for anti-inflammatory and anti-nociceptive activities. The anti-inflammatory activity was tested against egg albumin-induced edema, while the analgesic effects were studied using the acetic acid-induced writhing in mice and formalin test in mice. The results revealed that the aqueous extract of Ficus platyphylla possess significant, dose dependent anti-inflammatory effects. The extract also inhibited pain caused by acetic acid in mice and reduced pain episodes induced by formalin. The intraperitoneal LD50 in mice was 2000 mg kg. KEYWORDS. Analgesia, gamji, medicinal plant, oedema.
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[1] Ebersole, T., Esmond, R. & Schwartzman, R. June 2005 ; . Stem Cells--Patent Pools to the Rescue? Washington: Sterne, Kessler, Goldstein & Fox P.L.L.C. p. 1. [2] Clark, J., Piccolo, J., Stanton, B. & Tyson, K. December 2000 ; . Patent Pools: A Solution To The Problem Of Access In Biotechnology Patents? United States Patent and Trademark Office. p. 11. [3] Ebersole et al. pgs 3-4. [4] Arno, P. & Davis, M. "Why Don't We Enforce Existing Drug Price Controls? The Unrecognized and Unenforced Reasonable Price Requirements Imposed upon Patents Deriving in Whole or in Part from Federally Funded Research." Tulane Law Review, Vol. 75, p. 646. [5] The Economist. Technology Quarterly. December 2002 ; [19] Proposition 71, Sec. 3. [20] Ibid. [21] Ibid. [7] Gerth, J. & Stolberg, S. April 23, 2000 ; . "Medicine Merchants: Drug Companies Profit From Research Supported by Taxpayers." The New York Times. [8] Dembner, A, April 5, 1998 ; . "Public Handouts Enrich Drug Makers, Scientists." The Boston Globe. [9] Washburn, p. xi. [10] Washburn, pgs. 152-154. [11] Washburn, p. 151. [12] Goozner, M. 2005 ; . "Prizing Stem Cell Research. A New Paradigm for Managing Intellectual Property at the California Institute for Regenerative Medicine." p 8. Presented at the Joint Informational Hearing of the Senate Health Committee, Oct. 31, 2005, San Francisco. [22] Argument in favor of Proposition 71, from Official Voter Information Guide. [23] Baker, L. & Deal, B. September 2004 ; . Economic Impact Analysis. Proposition 71 California Stem Cell Research and Cures Initiative. Analysis Group. p. 2. [13] Esmond, R. & Schwartzman, R. June 2005 ; . "Stem Cells--The Patent Landscape". Smith. Kessler, Goldstein & Fox, PLLC. Washington, D.C. [14] Nelson, R. January 2001 ; "Observations on the Post-Bayh-Dole Rise of Patenting at American Universities." Journal of Technology Transfer. Vol. 26, p. 13. [15] Rai, A. & Eisenberg, R. 2003 ; . "BayhDole Reform and the Progress of Biomedicine." Law and Contemporar y Problems. Vol. 66, p. 292. [16] Rai & Eisenberg, pgs. 293-294. [17] Proposition 71, Sec.2. [18] Ibid.
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Continuing Pharmacy, Medicine and Nursing Education Program This educational activity awards 1 Category 1 CME credit, 1 contact hour nursing CNE, and 1 hour pharmacy CE 0.1CEU ; after you read the article on migraine prevention, complete the test and evaluation form, and return it by mail or fax prior to December 31, 2004. Goals and Objectives of the Continuing Education Program The goal of this program is to offer healthcare professionals the opportunity to develop knowledge, understanding and competency in the use of nutraceuticals. This continuing education program provides access to peer-reviewed studies on nutraceuticals, information that can be used to optimize their patients' and their own health and quality of life. Upon Completion of this Educational Program, Participants Will Be Able to: 1. Describe the proposed mechanism of action of feverfew as used for migraine prevention. 2. Identify the role of riboflavin and magnesium in the prevention of migraine. 3. Understand the pathophysiology of migraine. 4. Be familiar with the dosages, potential side effects, and drug interactions of feverfew, magnesium, and riboflavin. Receiving Credit After reading the CE-approved article in this edition of JANA, complete the test and evaluation form and return it to: American Nutraceutical Association CE Department 5120 Selkirk Drive, Suite 100 Birmingham, AL 35242 Fax: 205-991-9302 A CE CME certificate will be mailed or faxed to you. Please allow 30 days for receipt of the certificate. This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education ACCME ; through the joint sponsorship of the Foundation for Care Management and the American Nutraceutical Association. As an organization accredited by the WSMA Medical Education Committee to provide continuing medical education, the Foundation for Care Management certifies that this course meets the criteria for 1 Category 1 CME credit to satisfy the relicensure requirements of Washington State Medical Quality Assurance Commission and the AMA Physician's Recognition Award. The Foundation for Care Management is an approved provider of continuing education by the Colorado Nurses Association, an accredited approver by the American Nurses Credentialing Center's Commission on Accreditation. This program is approved for 1 contact hour of nursing CEU. Accreditation: The Department of Pharmacy, Broward General Medical Center, Fort Lauderdale, Florida is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Program # 187-999-03-008-H01 is approved for one hour .1 CEU ; of continuing pharmaceutical education credit. Disclosure Statement: The authors have no financial interests in any of the products mentioned in the article and effexor.
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The Local Organising Committee invites all members to experience something very special at ASM 2005, Canberra. The LOC are working with the National Scientific Advisory Committee to produce another superb Conference Program for you, with Plenaries, Symposia, Proferred Papers and Workshops. Here is an excellent opportunity to meet old friends and colleagues, network with many scientists and, most of all, enjoy a little of our National Capital. George McLean, Chair LOC ASM 2005 International Speakers include: Professor Margaret Hanmmerschlag, Director, Division of Paediatric Infectious Diseases, SUNY Downstate Medical Centre, New York, USA Professor Mark Chee, Genomics Illumina, San Diego CA, USA Professor James Staley, University of Washington, USA Dr Phillipe Sansonetti, Insititut Pasteur, Paris, France Professor Michael Danson, Centre for Extremophile Research, Department of Biology & Biochemistry University of Bath, UK Professor Alex van Belkum, Erasmus University Medical Centre, Department of Microbiology & infectious Diseases, Rotterdam, The Netherlands Professor Chris Whitfield, Canada Research Chair in Molecular Microbiology, University of Guelph, Ontario Canada Professor Sun Wen Chou, Veterans Affairs Medical Centre, Southwest US Veterans Hospital, Boston MA Dr Gaby Pfyffer, Department of Medical Microbiology, Institut fr Medizinische Mikrobiologie, Switzerland and furosemide.
Table 4 Difficulties in using acute and prophylactic migraine medications in the elderly * after 12 ; Drug Comments Acute medication: Ergots, triptans q Avoid in elderly patients with hypertension, coronary artery disease, peripheral vascular disease, cerebrovascular disease. Avoid in elderly with peptic ulcer disease. May have cognitive side effects. Elderly vulnerable to renal failure.
FRA. The internal consistency demonstrated is a reflection of the degree of correlation among the nine raters and the correlation of each individual item with the total score. A cut-off score of eight on the FRA yielded a sensitivity of 75% and a specificity of 82%. This cut-off score represents the maximum sensitivity and specificity, yet 25% of the fallers are not captured with this cut-off score. A cut-off score of six on the FRA yielded a sensitivity of 100%, but a specificity of only 33%. Using six as a cut-off score would capture all those, who fell in this sample, but might not capture all future fallers in the homebound population of older adults. HHA staff should be aware that while a cut-off score of eight is the most sensitive and specific, individuals with fewer identified risk factors may and do fall. Since the potential for not treating individuals at risk for falls is great, Perell et al. 2001 ; have suggested that in settings where the majority of patients are at high risk for falls, some measure of falls precautions and implementation of a fall prevention program may be appropriate. Perell also reported that in an analysis of 15 fall-risk assessment tools, sensitivity reported ranged from 43% to 100% and specificity reported ranged from 38% to 96% for the nursing and functional assessment tools Perell, 2001 ; . The Berg Balance Test Berg, 1989 ; exhibited a sensitivity of 77% and specificity of 86% with testing, while the POMA has been shown to have a sensitivity of 80% and specificity of 74%, respectively Tinetti et al., 1986 ; . The sensitivity and specificity of the FRA fall within the ranges of these widely accepted tools. Chi-square testing did not show that gender, living status living alone ; , age 80, use of four more medications or two or more specific medications ; , environmental hazards, mental status changes, decreased lower extremity strength, reduced vision, and incontinence varied significantly between faller and non-fallers. Thus the results of this study were not completely consistent with the findings of other researchers who have examined fall-risk in the over 65 population "Clinical Practice Guidelines: The prevention of falls in older persons, " 2001 ; . In the current homebound population studied, the majority of both groups fallers non-fallers ; had multiple medications and exhibited decreased lower extremity strength. Similar percentages within faller and nonfaller homebound groups were also noted for the presence of mental status changes, decreased vision, environmental hazards, living status, and age 80. It was difficult to accurately assess the impact of living status in this study, since many subjects who were identified as living alone had regular help, while some individuals living within assisted living centers were left alone for periods of time during the day and gemfibrozil and diovan, for example, diovan used for.
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